Drug related problems among cervical cancer : A prospective study

• Abhishek Hanumant Khaire,  
• Esha Alpesh Patel,  
• Sumedha Anil Savane,  
• Avinash Santosh Shinde,  
• Anjali Ramakant Kumbhar,*  
• Asma Pathan

Abstract

Background: Drug-related problems (DRPs) are defined as drug-related events that interfere, either directly or indirectly, with the patient receiving the best possible medical care. Aim and Objective: Study is performed to assess the drug related problems in cancer treatment of women with uterine cervix carcinoma. Methods: A prospective study was carried out in women aged 20- 79 years were examined who were receiving for chemotherapy uterine cervix carcinoma on weekly basis at Indrayani Hospital and Cancer Institute to look at drug-related issues. Results: 54 patients had a total of 365 drug related problems (DRPs) identified. The most common DRPs were medication interactions (136, 37.26%), adverse drug responses (201, 55.06%), and non-adherence to treatment (14, 3.83%). ADRs including leucopenia, anemia, nausea, vomiting, and fatigue were the most frequent. Conclusion: The most common DRPs were drug interactions, adverse drug reactions, and the requirement for laboratory monitoring. Adequate oversight and execution of clinical pharmacy services will undoubtedly aid in the optimization of drug-related issues.

Keywords

Uterine Cervix Carcinoma, Carboplatin, Drug Related Problems, Drug interactions and Adverse drug reaction.