Sclerosing Stromal Tumor in a Young Female : Clinical Presentation and Management

• DR TIRUVAIPATI SIRI MADHURI,*  
• DR NIDHI SHARMA

Abstract

Background: Sclerosing stromal tumors (SSTs) are rare ovarian neoplasms predominantly affecting young females during their second or third decade of life. This case report presents a comprehensive analysis of a young female patient diagnosed with an ovarian SST, highlighting its clinical presentation, histopathological characteristics, and management. Clinical Presentation: The emergence of SSTs poses diagnostic challenges due to their rarity and varied clinical manifestations, often mimicking other ovarian neoplasms. Patients typically present with nonspecific symptoms such as abdominal pain, bloating, and irregular menstrual cycles. Imaging studies and histopathological examination are essential for accurate diagnosis. Histopathological Characteristics: Histologically, SSTs are characterized by a proliferation of fibrous stromal cells interspersed with varying degrees of collagen deposition and hyalinization, posing a diagnostic challenge. Immunohistochemical analysis plays a pivotal role in confirming the diagnosis. Management: Surgical resection remains the cornerstone of management, with the aim of complete excision while preserving ovarian function whenever possible. Frozen section analysis during surgery aids in intraoperative decision-making. Adjuvant therapy is generally not indicated due to the benign nature of SSTs. Conclusion: A multidisciplinary approach involving gynecologists, pathologists, and radiologists is crucial for accurate diagnosis and optimal management of SSTs, ensuring favorable outcomes for affected patients. Continued research efforts are warranted to further elucidate the underlying pathogenesis of SSTs and refine treatment algorithms for these rare entities.

Keywords

Keywords: Sclerosing stromal tumor, ovarian neoplasm, young female, diagnosis, management.