The role of salivary uric acid as predictive marker for preeclampsia in comparison with serum uric acid

• sarah ismael,  
• shatha sami hussein,*  
• manal madany abdulqader

Abstract

Aim & Objective To evaluate the role of salivery uric acid in PET versus normal pregnancy in comparison with serum uric acid. Background/Introduction Pregnancy may be complicated by many medical disease which convert the pregnancy to high risk one, many effort try to decrease the complication by early detection once, and by safe non invasive test another. Material and methods: The study involved 180 patient divided into three group 60 patient healthy not pregnant women as control, 1st study group (A) 60 normotensive pregnant women in third trimester, 2nd study group (B) 60 patient diagnosed as PET both group in their third trimester of pregnancy, uric acid levels in both the serum & saliva was recorded by ELISA and the result was compared statistically. A cross-sectional study performed at AlYarmouk Teaching Hospital from October 2022 to October 2023. Result The result show when compare serum and salivary uric acid level in the three studying groups the mean of serum uric acid level were46.65±6.76mg/dl, 50.03±6.28mg/dl, 63.31±3.61 mg/dl in the non pregnant,pregnant,pregnant with PET consequently with obvious difference P-value 0.0001 . Salivary uric acid was significantly increased in the pregnant PET group mean level was (50.59-83.58mg/dl) in comparison with (33.95-63.11mg/dl)in non pregnant and (38.94-66.93mg/dl) in pregnant group were the p- value 0.0001 Conclusion Salivary UA can be used as a simple non invasive test to monitor women with preeclampsia. Keywords salivary uric acid, preeclampsia ,serum uric acid.

Keywords

salivary uric acid,preeclampsia ,serum uric acid