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Colloseum to estimate the accuracy of detection of cervical intraepithelial neoplasia using electrical impedance spectroscopy with colposcopy- A one year study

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Original Article

Author Details : Shalini Vasudeva, Ragini Thapa*

Volume : 8, Issue : 2, Year : 2021

Article Page : 166-171

https://doi.org/10.18231/j.ijogr.2021.037

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Abstract

Background: Cervical cancer is ranked as the second most common cancer amongst women worldwide and in many low-income countries, it is the most common female cancer. ZedScan, enables us to have a first hand estimation of the accuracy of the system and thereby settling and verifying the claims of the manufacturer.
Aim: To prove, easy detection of cervical carcinoma by using EIS as an adjunct to colposcopy giving better detection rates in (CIN)cervical intraepithelial neoplasm with increased diagnostic accuracy.
Materials and Methods: It was a prospective study done on a sample size of 200 patients. The patients were selected from amongst all the patients attending the Department of Obstetrics & Gynaecology, Base Hospital, Delhi Cantt, either with a clinical indication or an abnormal cervical cytology. All such cases were recruited into the study with histopathology as a gold standard.
Results: Age of patients ranged from 30 to 68 years. Majority of women were aged between 31-40 years (n=135; 67.5%). Mean age of patients was 37.486.3 years. Almost all (98.5%) the test patients were married. There were 3 (1.5%) widowed/divorced women. Majority of women were educated up to graduation or above (51%) followed by those educated upto 8th standard (n=53; 26.5%) and those educated upto secondary level (22.5%). BMI of women ranged from 20.11 to 32.30 kg/m2. Majority were
in overweight category (n=113; 56.5%). A total of 72 (36%) had normal weight and 15 (7.5%) were obese. Socioeconomically, 88 (44%) belonged to upper middle, 74 (37%) lower middle, 35 (17.5%) to lower and 3 (1.5%) to upper socioeconomic class. Histopathologically, a total of 26 cases were positive and 174 were negative. As compared to histopathology, ZedScan had 11 true positive, 5 false positive, 15 false negative and 169 true negative cases. Correspondingly, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy value of ZedScan for any grade of neoplasia was 42.3%, 97.1%, 68.8%,
90.9% and 90% respectively.
Conclusion: The findings of the study conducted thus suggest that ZedScan has a useful role as an adjunct to Colposcopy in the detection of cervical neoplasia, particularly that of high-grade CINs.

Keywords: CIN, Electrical impedance spectroscopy, ZedScan.

How to cite : Vasudeva S , Thapa R , Colloseum to estimate the accuracy of detection of cervical intraepithelial neoplasia using electrical impedance spectroscopy with colposcopy- A one year study. Indian J Obstet Gynecol Res 2021;8(2):166-171

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