Indian Journal of Obstetrics and Gynecology Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-2746
Online ISSN: 2394-2754
CODEN : IJOGCS
Indian Journal of Obstetrics and Gynecology Research (IJOGR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 9, Issue : 2, Year : 2022
Article Page : 193-197
https://doi.org/10.18231/j.ijogr.2022.038
Abstract
Background: Corona virus outbreak emerged in Wuhan in late December 2019. It was declared as pandemic by WHO in March 2020. Patients usually present with fever cold, cough and fatigue. The severity of the disease varies from moderate to severe, with the majority of cases being mild. Fatality was high in immuno-compromised patients. Pregnancy is considered to be an immunosuppressive state, so pregnant women were also at risk of acquiring COVID-19 infection. According to the literature, COVID-19 infection during pregnancy may cause fetal discomfort, preterm labour, miscarriage, or neonatal death.
Materials and Methods: This is an observational analytical study that took place over an 8-months period during which the hospital served as a nodal centre for Covid patients. All pregnant women with intrauterine death at 20 weeks or more of pregnancy with COVID-19 infection confirmed through RTPCR were included in the study Placental fragments and amniotic fluid were tested for SARS-COV2 infection. Histology of placental fragments were studied by pathologist.
Results and Conclusion: Out of 30 Intrauterine deaths reported during the study period only twelve of them are due to associated co-morbidities like hypertensive disorders, diabetes and others, remaining are due to COVID-19 related hypoxia. Fetal demise with no other clinical or obstetric disorders prove that intrauterine deaths is also an outcome in pregnancies with COVID-19 infection with signs of acute chorioamnionitis and other inflammatory reactions noted in histological specimen of placental fragments.
Keywords: COVID- 19, Intrauterine fetal death, Placental histopathology.
How to cite : Malavika K, Vellanki J, Intrauterine deaths in pregnancies with COVID-19 infection. Indian J Obstet Gynecol Res 2022;9(2):193-197
This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
