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A stockpile of neonatal antibodies pertaining to SARS Covid (COVID 19) ascertained in cord blood after complete vaccination of covishield in mother- An observational study

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Original Article

Author Details : Abhishek S Krishna*, Adithya S L , Ahalya U , Akhila Anil, Amal A , Shaiju S Dharan

Volume : 10, Issue : 4, Year : 2023

Article Page : 469-473

https://doi.org/10.18231/j.ijogr.2023.089

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Abstract

Background: Maternal antibodies are a vital component of neonatal immunity. These antibodies give the baby a head start in building their immune system and fighting off diseases. The study was carried out to check the presence of IgG antibodies in cord blood of a completely vaccinated mother with Covishield and to find out if any side effects occurred during their vaccination. It was clear from the study that all the cord blood samples showed presence of antibodies and only limited side effects were observed in the vaccinated mothers.
Materials and Methods: An observational study was done in the gynecology department of a tertiary care hospital in Trivandrum from November 2022 to April 2023 (6 months duration) with 40 cord blood samples taken from completely vaccinated mothers.
Results: A total of 40 women were included who had completed two doses of Covishield vaccine. Presence of umbilical cord blood IgG was found in all the 40 samples, i.e. Covid IgG > 17.8 BAU/mL. Among the 40 samples, 75% of them had not experienced any side effects after their vaccination while the remaining 25% had experienced minor side effects.
Conclusion: The findings made from this study can be used to prove that vaccines are capable of producing antibodies in mother which will be transferred to her baby through the cord blood. It is also evident that the vaccine has produced only minor side effects.
 

Keywords: COVID- 19, Vaccination, Covishield, Cord blood, ECLIA.

How to cite : Krishna A S, Adithya S L, Ahalya U, Anil A, Amal A, Dharan S S, A stockpile of neonatal antibodies pertaining to SARS Covid (COVID 19) ascertained in cord blood after complete vaccination of covishield in mother- An observational study. Indian J Obstet Gynecol Res 2023;10(4):469-473

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