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A comparative study between dinoprostone pessary and dinoprostone gel for induction of labor and neonatal outcome

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Original Article

Author Details : Rashmi M D , Pranjali Rai*

Volume : 11, Issue : 2, Year : 2024

Article Page : 167-171

https://doi.org/10.18231/j.ijogr.2024.035

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Abstract

Aims and Objectives: This study compares the safety and efficacy of two dinoprostone formulations – a pessary and a gel.
Materials and Methods: A retrospective randomised observational study was conducted to compare Dinoprostone controlled release pessary and Dinoprostone gel for induction of labor at term in women with unfavourable cervix at Apollo Hospitals BGS, Mysuru during August 2018 – May 2020. Among study participants 50 expectant mothers received Dinoprostone pessary while 50 women received Dinoprostone gel for induction of labour. Both groups were compared and the outcomes were analysed. The primary outcomes of the study were induction to delivery interval, successful vaginal delivery, need for operative vaginal delivery and need for caesarean section. Secondary outcomes were observed for neonatal morbidity and uterine hyperstimulation.
Results: There was a significant (p=<0> Conclusion: Both formulations of dinoprostone are safe for induction of labor at term. However, pessary achieves comparitively a higher rate of spontaneous vaginal delivery with a shorter labor induction time. Ease of administration, single application and thus decreased chance of infections are its additional benefits.
 

Keywords: Induction of labor, Prostaglandins, Dinoprostone, PGE2 pessary, PGE2 gel, Cervical ripening, Vaginal pessary.

How to cite : Rashmi M D, Rai P, A comparative study between dinoprostone pessary and dinoprostone gel for induction of labor and neonatal outcome. Indian J Obstet Gynecol Res 2024;11(2):167-171

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