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Uncovering ovarian reserve: Insights into hormones, lipids, and essential metals

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Original Article

Author Details : Shefali Singh, Rupita Kulshrestha*, Juhi Verma, Vibhav Nigam, Manish Raj Kulshrestha

Volume : 11, Issue : 2, Year : 2024

Article Page : 226-231

https://doi.org/10.18231/j.ijogr.2024.045

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Abstract

Background: Polycystic Ovary Syndrome (PCOS) is an endocrine disorder prevalent in women of reproductive age group. The intricate nature of PCOS development is highlighted by fluctuations in various sex hormones, such as luteinizing hormone(LH), follicle-stimulating hormone and prolactin.
Objective: This study aims to assess the lipid profile levels, vital metals and sex hormones in the serum of patients with PCOS and contrast these findings with normal controls.
Materials and Methods: The study analyzed health metrics between 57 women with PCOS and 57 normal controls. The lipid profile was assessed using Beckman Coulter AU480. Sex hormones were estimated using Roche Diagnostics Cobas 6000. Inductively coupled plasma mass spectrometry (ICPMS) was used to measure the essential trace metals, including magnesium (Mg), copper (Cu) Selenium (Se) and zinc (Zn).
Results: The PCOS patients exhibited significantly elevated levels of LH (9.52 vs 3.48, p<0 p=0.03) R=0.27, p=0.045) R=0.76, p=0.030).> Conclusion: In patients with PCOS, LH, FSH, and prolactin levels were found to be increased. A correlation was observed between Se and AMH, and a relationship was noted between LH and HDL. Selenium appears to have a significant influence on the ovarian reserve.
 

Keywords: Polycystic ovary syndrome, Sex hormone, Lipid profile, Essential metals.

How to cite : Singh S, Kulshrestha R, Verma J, Nigam V, Kulshrestha M R, Uncovering ovarian reserve: Insights into hormones, lipids, and essential metals. Indian J Obstet Gynecol Res 2024;11(2):226-231

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