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Serum human pregnancy specific glycoprotein 1 in pregnant women with preeclampsia in comparison with normal pregnancy

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Original Article

Author Details : Ali Mohamed Murad, Ban Hussein Ibraheem, Sarah Ismael Ali, Shatha Sami Hussein*, Liqa Ameer Saad

Volume : 11, Issue : 3, Year : 2024

Article Page : 388-392

https://doi.org/10.18231/j.ijogr.2024.070

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Abstract

Objectives: To compare the serum pregnancy specific glycoprotein 1 values of women with preeclampsia with the values of healthy pregnant women.
Materials and Methods: A total of 90 pregnant women, whom were recruited during their antenatal care visits to the obstetrical department in Hospital, were included. They were divided into two groups: 45 women with diagnosis of preeclampsia and 45 controls who were the women with healthy pregnancy. Blood samples were collected from both groups and the measurement of pregnancy specific glycoprotein 1 was done using an enzyme immunometric assay.
Results: The groups of preeclampsia pregnant women had markedly lower pregnancy specific glycoprotein 1 than the women with the uneventful pregnancies (9.8±3.8 vs 14.3±6.0 ng/ml; p value <0> Conclusion: Pregnancies complicated by preeclampsia are associated with decreased maternal serum level of pregnancy specific glycoprotien. This abnormally decreased levels of might be a reflection of stressed or dysfunctional syncytiotrophoblasts, which is related to the pathogenesis of this placental disorder.
 

Keywords: Preeclampsia, Pregnancy specific glycoprotein.

How to cite : Murad A M, Ibraheem B H, Ali S I, Hussein S S, Saad L A, Serum human pregnancy specific glycoprotein 1 in pregnant women with preeclampsia in comparison with normal pregnancy. Indian J Obstet Gynecol Res 2024;11(3):388-392

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