---

Significance of leukocyte and platelet counts in hypertensive disorders of pregnancy - A retrospective study in a tertiary care hospital

---

Original Article

Author Details : Veena S R*, Satish Korah Kuruvila

Volume : 11, Issue : 3, Year : 2024

Article Page : 398-402

https://doi.org/10.18231/j.ijogr.2024.072

Suggest article by email

Get Permission

---

Abstract

Background: Hypertensive disorders in pregnancy are a spectrum of disorders ranging from gestational hypertension, pre-eclampsia to eclampsia and chronic hypertension superimposed by pre-eclampsia. With an incidence of 7-15% complicating pregnancies, several theories have been stated to define the pathogenesis. Inflammation per se is also found to have its part in the pathogenesis of hypertension.
Objective: To evaluate and compare the inflammatory mediators namely the leukocyte count, platelet count, absolute neutrophil count, absolute lymphocyte count, neutrophil lymphocyte ratio and platelet lymphocyte ratio among the hypertensive disorders in pregnancy.
Materials and Methods: This is a retrospective study done at a tertiary care hospital including all women admitted with hypertension in pregnancy from 26th April 2016 to 31 March 2019. Patients with singleton pregnancy with hypertension were included and those with prelabour rupture of membranes or concomitant infection were excluded. Patients were divided into four groups, chronic hypertension, and gestational hypertension, non-severe and severe preeclampsia. The total and differential leukocyte counts at admission were accessed from the medical records and statistical analysis was done.
Results: Out of 4860 deliveries, 294 patients were diagnosed with hypertensive disorders (6.04%). Of the 294, those belonging to chronic hypertension, gestational hypertension, non-severe and severe preeclampsia were 43 (14.6%), 128(43.5%), 52(17.7%) and 71(24.1%) respectively. A p value of < 0>

Keywords: Hypertension, Total leukocyte count, Pregnancy, Preeclampsia

How to cite : Veena S R, Kuruvila S K, Significance of leukocyte and platelet counts in hypertensive disorders of pregnancy - A retrospective study in a tertiary care hospital. Indian J Obstet Gynecol Res 2024;11(3):398-402

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.