Indian Journal of Obstetrics and Gynecology Research

Print ISSN: 2394-2746

Online ISSN: 2394-2754

CODEN : IJOGCS

Indian Journal of Obstetrics and Gynecology Research (IJOGR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...

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Case Series


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673-679


Authors Details

Rita Yadav*, Malti K Maurya, Mala Sagar, Shailendra Kumar


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Case series of pure mucinous breast carcinoma: A rare histopathological subtype


Case Series

Author Details : Rita Yadav*, Malti K Maurya, Mala Sagar, Shailendra Kumar

Volume : 11, Issue : 4, Year : 2024

Article Page : 673-679

https://doi.org/10.18231/j.ijogr.2024.122



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Abstract

Pure mucinous breast carcinoma (PMBC) is even rarer and accounts for about 2% of all primary breast carcinoma. It is composed entirely of tumour cells with abundant extracellular mucin and without admixing of infiltrating ductal carcinoma. We studied a total of ten cases of Pure Mucinous Breast Carcinoma. Here we describes each case of demographic features and histopathological features of PMBC. The results of immunohistochemistry of Estrogen receptor (ER), Progesterone receptor (PR), Human epidermal growth factor receptor 2(HER-2neu) were also noted in this case series. All the cases were female and above 50 years of age. Out of 10 cases, 6 cases have the tumour’s location on the left side of the breast and 4 cases have the tumour’s location on the right side of the breast. All the cases belong to the lower grading and staging of the tumour. Only one case had positive lymph node status.Hormone receptor status of all the cases has ER & PR positive expression, HER-2neu negative expression and low Ki 67 labelling index. To conclude, PMBC was associated with lower-grade tumours, lower-stage, infrequent lymph node metastasis and luminal type A hormonal receptor status. These favourable findings suggest that PMBC has a better prognosis and may give a better response to hormonal therapy.
 

Keywords: Mucinous carcinoma, Pure, Breast, Immunohistochemistry, Histopathology.


How to cite : Yadav R, Maurya M K, Sagar M, Kumar S, Case series of pure mucinous breast carcinoma: A rare histopathological subtype. Indian J Obstet Gynecol Res 2024;11(4):673-679

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