Print ISSN: 2394-2746
Online ISSN: 2394-2754
CODEN : IJOGCS
Indian Journal of Obstetrics and Gynecology Research (IJOGR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 3, Issue : 3, Year : 2016
Article Page : 264-266
Abstract
Introduction: Viral hepatitis is one of the commonest causes of jaundice in pregnancy. Hepatitis E viral (HEV) infection is associated with major catastrophes in pregnancy with high maternal and foetal mortality rate.
Objectives: To determine the prevalence of HEV infection in pregnancy and to study maternal and foetal outcome in acute HEV and non HEV infection.
Material and Methods: This was a prospective observational study, conducted at SAIMS obstetrics department over a period of 2 years, June 2011-June 2013, among pregnant women presented with features of acute viral hepatitis like nausea, vomiting, jaundice, fever etc. These women were further investigated and those who were found to be positive for infection with HAV, HBV and HEV were further studied in view of maternal and foetal outcome.
Results: Pregnant women who were found to be suffered from acute viral hepatitis were twenty five. Majority of women were unbooked (90%) with mean age of 23±3.5years, most of them were presented in third trimester with mean gestational age of 31.33±3.5 weeks. Primigravida (58%) forms the largest group. Infective pathology due to HEV was 84% and 16% due to HAV and none of the patients were found to be acutely infected with HBV, HCV. HEV infected patients found to have high rate of complications as compared to non HEV infected patients. HEV infected patients had high rate of abortion (4.7%), fulminant hepatic failure (23.8%), Disseminated intravascular coagulation (33%), acute respiratory distress syndrome (14.28%), hepatic encephalopathy (23.8%), acute renal failure (9.52%), intrauterine foetal demise (35.29%), low birth weight (84.6%), NICU admission rate and preterm labour as compared to non HEV infected patients.
Conclusion: Acute hepatitis E viral infection in pregnancy carries a poor maternal and foetal outcome as compared to other viral hepatitis causative agents.
Keywords: Hepatitis, HEV infection
How to cite : Jain P G, Sapre S, Fetomaternal Outcome in Acute Viral Hepatitis. Indian J Obstet Gynecol Res 2016;3(3):264-266
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