Indian Journal of Obstetrics and Gynecology Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-2746
Online ISSN: 2394-2754
CODEN : IJOGCS
Indian Journal of Obstetrics and Gynecology Research (IJOGR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 5, Issue : 3, Year : 2018
Article Page : 327-330
https://doi.org/10.18231/2394-2754.2018.0075
Abstract
Introduction: The prevalence of Gestational diabetes mellitus (GDM) is high in Asian subcontinent. As per current guidelines, the routine screening for GDM is at 24 to 28 weeks of gestation.30 to 50% of GDM cases may remain undiagnosed until such period of screening. This study aims to investigate HbA1C levels at as early as 12 weeks of pregnancy as a predictor of GDM.
Materials and Methods: This prospective study included 100 patients enrolled at their first antenatal visit, or before 12 weeks of gestational age, who attended OPD. At the time of enrolment for HbA1c and routine antenatal investigations were done. A 75 gm GTT was done at 22 to 26 weeks of gestation. HbA1c cutoff was taken as ?5.7 & ?6.4 and patients having value ?5.7 were taken as abnormal. Subjects with HbA1c ?6.5, overt diabetes, hemoglobinopathies, anaemia, chronic renal diseases and multiple pregnancies were excluded from the study.
Results: It is found that women >28 years had higher levels of hbA1C in comparison to patients <28> Conclusion: The study concludes that women with higher HbA1c (?5.7) were more likely to develop GDM than those women with lower HbA1C (?5.7). HbA1c can be done routinely in early pregnancy (1st trimester). Women with higher HbA1c (?5.7) can benefit from early interventions early in pregnancy thereby prevent GDM and adverse perinatal and pregnancy outcomes.
Keywords: Early pregnancy, Glycated hemoglobin, GDM, Maternal age.
How to cite : Sujithra. D., Mukherjee S, Sudha S, Glycated hemoglobin in early pregnancy as a predictor of gestational diabetes mellitus. Indian J Obstet Gynecol Res 2018;5(3):327-330
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