Carcinosarcoma of the fallopian tube is a rare and aggressive malignancy accounting for less than 4% of all gynecologic carcinosarcomas. This case report details a 65-year-old woman with primary fallopian tube carcinosarcoma who presented with abdominal distension and discomfort. Diagnostic imaging revealed bilateral hypermetabolic ovarian masses with peritoneal and mesenteric metastasis. Histopathological analysis showed a biphasic neoplasm with high-grade serous papillary areas and chondrosarcomatous regions with brisk mitotic activity and Serous Tubal Intraepithelial Carcinoma (STIC) in the tubal lining. The patient underwent neoadjuvant chemotherapy, cytoreductive surgery, and follow-up chemotherapy. The rarity and aggressive nature of fallopian tube carcinosarcomas emphasize the importance of documenting and sharing cases to enhance understanding of diagnosis and treatment. Future research should focus on improving diagnostic techniques and exploring more effective treatment options.
Keywords: Carcinosarcoma, Fallopian tube, Serous tubal intraepithelial carcinoma.