Indian Journal of Obstetrics and Gynecology Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-2746
Online ISSN: 2394-2754
CODEN : IJOGCS
Indian Journal of Obstetrics and Gynecology Research (IJOGR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 11, Issue : 4, Year : 2024
Article Page : 591-594
https://doi.org/10.18231/j.ijogr.2024.106
Abstract
People with thalassemia trait should be distinguished from those who have anemia due to iron deficiency since they typically have mild microcytic hypochromic anemia and are mostly asymptomatic.
Objective: To evaluate efficacy of Mentzer index for screening Beta- Thalassemia trait in pregnant women.
Materials and Methods: From January 2023 to October 2023, the observational study was carried out in the Department of Gynecology & Obstetrics at Sri Guru Ram Das Charitable Hospital Amritsar. The study comprised 130 pregnant women with anemia. To assess microcytic hypochromic anemia, tests like complete blood count (CBC), peripheral blood smears, iron studies, and hemoglobin electrophoresis were performed. Mentzer Index (MI) was computed, and its specificity and sensitivity assessed.
Reslut: Of the 130 patients, 112 had Mentzer Index greater than 13 and 18 had Mentzer Index less than 13 but only 12 out of these18 had beta thal-trait according to HPLC. There were total 15 females having beta thal-trait as per HPLC, however 3 of the 15 had Mentzer >13. Conserding Beta thal-trait, the Mentzer Index's sensitivity and specificity were 80% and 95.65% in this study, and 95.33% and 86.96% for IDA.
Conclusion: Mentzer Index (MI) is a helpful tool to distinguish iron deficiency from thalassemia trait as its specificity and sensitivity is high as electrophoresis in diagnosis. In situations with limited resources, this proves to be advantageous in terms of cost-effectiveness.
Keywords: Mentzer Index, Beta thalassemia trait, IDA 1.
How to cite : Kaur S, Pahwa S, Kakkar S, Kaur J, Evaluation of efficacy of mentzer index for screening of beta - Thalassemia trait in antenatal women. Indian J Obstet Gynecol Res 2024;11(4):591-594
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