Indian Journal of Obstetrics and Gynecology Research
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Print ISSN: 2394-2746
Online ISSN: 2394-2754
CODEN : IJOGCS
Indian Journal of Obstetrics and Gynecology Research (IJOGR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...Original Article
Author Details :
Volume : 3, Issue : 4, Year : 2016
Article Page : 352-355
Abstract
Background: To study the effect of IV labetalol in hypertensive emergencies in pregnancy and their effects on maternal and Perinatal outcome. Pregnant women with blood pressure >160/110 mmHg were subjected to the trial. Patients were randomized to receive intravenous labetalol injection (in an escalating dose regimen of 20, 40, 80, 80 and 80 mg) every 15 minutes until the target blood pressure of <150/100 mmHg was achieved. Addition of nifedipine treatment was done if the initial treatment regimen was unsuccessful. Primary and secondary outcomes like the time interval and number of doses required to achieve a blood pressure of ?150/100 mmHg and adverse effects of the antihypertensive agents were reported.
IV Labetalol is effective in sustaining therapeutic level.
Objective: To study the efficacy of IV Labetalol in management of hypertensive emergencies in pregnancy and adverse effects of labetalol.
Materials and methods: A prospective observational study of 60 cases with hypertension in pregnancy, treated with Labetalol, was conducted over a period of one and half years.
Results: The effective control of blood pressure with the use of Labetalol in the dosage used, was observed in cases of moderate to severe pregnancy induced hypertension.
Conclusion: Intravenous labetalol is an effective and safe drug in the management of hypertension in pregnancy.
Keywords: Hypertension, Pregnancy, Labetalol
How to cite : Omkara Murthy K, Dhananjaya Bs, Jamuna R, Chaitra R, Intravenous Labetalol in management of Hypertensive Emergencies in Pregnancy. Indian J Obstet Gynecol Res 2016;3(4):352-355
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