TO STUDY THE IMMEDIATE COMPLICATIONS AND CLINICAL OUTCOME OF NEWBORNS WITH MECONIUM-STAINED AMNIOTIC FLUID; A CROSS-SECTIONAL STUDY

Authors: Dr.Suryakant sayanna Mundlod, Dr.Rhea m singh, Dr.Srushti suhas jadhav, DR Deepali abhijeet Ambike, Dr.Rajesh Kishanrao Kulkarni, Dr. Sandhya a Haribhakta, Dr.Seema p Soni, Dr.Smita marotirao thakkarwad, dr vinay k patil, Dr.Nimisha s Moni, Dr Kalyani m Parihar

DOI: 10.18231/j.ijogr.8967.1762144976

Keywords: Keywords: Meconium-stained amniotic fluid; staging; outcome, neonate

Abstract: Background: The incidence of meconium-stained amniotic fluid (MSAF) during labor has long been considered the predictor of adverse neonatal outcomes. It has recently been reported that neonatal morbidity and mortality correlate with the degree of meconium thickness. Material and methods: This prospective study was done at a tertiary care teaching hospital. Babies born to mothers with meconium-stained liquor were enrolled as per inclusion criteria. Newborns were allocated in thin and thick MSAF groups based on the color and thickness of the amniotic fluid. A total of 174 babies were enrolled. Data related to their clinical course and outcome was collected in a predesigned proforma. Analysis was performed by applying students' t-test and Chi-square test. Results: A total of 174 neonates born to mothers with meconium-stained amniotic fluid were included in the study. The mean gestational age was 37.6+2.1 weeks. 51.4% were delivered by vaginal delivery. 73% (127) had thick meconium and 27% (47) had thin meconium. Of all babies with meconium-stained amniotic fluid, 139 (80%) required admission to NICU as only 35 (20%) were shifted to the mother's side. Babies with thick MSL had a significantly longer duration of NICU stay than those with thin MSL (p value<0.001) and required invasive ventilation (p<0.001). In our study, 119 of 127 (93%) babies with thick MSL and 42 of 47 (89%) babies with thin MSL were discharged. 8 (6%) of the babies with thick and 5 with thin MSL had mortality. Conclusion: Thick MSL, compared to thin MSL, was associated with a higher need for NICU admission, as well as with a longer duration of NICU stay and the need for invasive ventilation.