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- DOI 10.18231/j.ijogr.v.12.i.3.2
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CrossMark
- Citation
Uterine artery embolization: A novel frontier in the treatment of caesarean scar pregnancy
- Author Details:
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Jothikala Chellamuthu
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Gomathi Meignanamoorthy
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Jamila Hameed *
This study aims to analyse the outcome of UAE treatment in CSP population to calculate the overall success rate. Caesarean scar pregnancy (CSP) is an infrequent ectopic pregnancy now more frequently associated with increasing rates of caesarean section, which are associated with significant morbidity, such as haemorrhage and uterine rupture. Early ultrasound diagnosis is critical for treatment, whereas uterine artery embolization (UAE) has been effective in managing CSP recurrences and prevented serious complications.
A comprehensive search across PubMed, Google Scholar and Scopus yielded 4844 records out of which 9 studies were finally selected of which 8 studies were selected for meta analyses. SPSS version 28 and R Studio were used for data analysis and graph preparation respectively. The overall success rate was 94.61% in a total of 3688 UAE treated CSP patients. UAE proved to be effective with promising success rates.
References
- Sadeghi H, Rutherford T, Rackow BW, Campbell KH, Duzyj CM, Guess MK, et al. Cesarean scar ectopic pregnancy: case series and review of the literature. Am J Perinatol. 2010;27(2):111–20.
- Jiao LZ, Zhao J, Wan XR, Liu XY, Feng FZ, Ren T, et al. Diagnosis and treatment of cesarean scar pregnancy. Chinese Medical Sciences Journal. 2008;23(1):10–5.
- Hameed MS, Wright A, Chern BSM. Cesarean Scar Pregnancy: Current Understanding and Treatment Including Role of Minimally Invasive Surgical Techniques. Gynecol Minim Invasive Ther. 2023;12(2):64–71.
- Timor-Tritsch IE, Monteagudo A, Bennett TA. Cesarean Scar Pregnancy: A baby placenta Accreta. In: First-Trimester Ultrasound: A Comprehensive Guide. Cham: Springer International Publishing; 2023. p. 339–69.
- Michener C, Dickinson JE. Caesarean scar ectopic pregnancy: a single centre case series. Aust N Z J Obstet Gynaecol. 2009;49(5):451–5.
- Glenn TL, Bembry J, Findley AD, Yaklic JL, Bhagavath B, Gagneux P, et al. Cesarean Scar Ectopic Pregnancy: Current Management Strategies. Obstet Gynecol Surv. 2018;73(5):293–302.
- Tower AM, Frishman GN. Cesarean scar defects: an underrecognized cause of abnormal uterine bleeding and other gynecologic complications. J Minim Invasive Gynecol. 2013;20(5):562–72.
- Armstrong V, Hansen WF, Van Voorhis BJ, Syrop CH. Detection of cesarean scars by transvaginal ultrasound. Obstet Gynecol. 2003;101(1):61–5.
- Feng C, You L, Zhu X. Differential Diagnostic Value of Two- dimensional Ultrasound Combined with Three-dimensional Ultrasound Imaging Technology for Cesarean Scar Pregnancy. Curr Med Imaging. 2024;20(1):e15734056262717.
- Zhang B, Jiang ZB, Huang MS, Guan SH, Zhu KS, Qian JS, et al. Uterine artery embolization combined with methotrexate in the treatment of cesarean scar pregnancy: results of a case series and review of the literature. J Vasc Interv Radiol. 2012;23(12):1582–8.
- Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71.
- Wells G, Shea B, O’connell D, Peterson J, Welch V, Losos M, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Ottawa: University of Ottawa; 2014. 368 Chellamuthu et al. / Indian Journal of Obstetrics and Gynecology Research 2025;12(3):362–368
- Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta- analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629–34.
- Stanley TD, Jarrell SB. Meta‐regression analysis: a quantitative method of literature surveys. J Econ Surv. 2005;19(3):299–308.
- Guo MH, Wang MF, Liu MM, Qi F, Qu F, Zhou JH, et al. Management of cesarean scar pregnancy: A case series. Chin Med Sci J. 2015;30(4):226–30.
- Chen ZY, Li XY, Zhao D, Zhou M, Xu P, Huang XF, et al. Clinical analysis on hysteroscopic surgery for the treatment of type Ⅱ cesarean scar pregnancy in the first trimester. Zhonghua Fu Chan Ke Za Zhi. 2017;52(10):669–74.
- Wang J, Hu Y, Ye C. Observation on the Effect of Uterine Artery Embolization Combined with Hysteroscopy in the Treatment of Cesarean Scar Pregnancy. In: 2018 International Conference on Medicine Sciences and Bioengineering (ICMSB 2018). 2018. p. 75–
- Cao S, Qiu G, Zhang P, Wang X, Wu Q. A comparison of transvaginal removal and repair of uterine defect for type II Cesarean scar pregnancy and uterine artery embolization combined with curettage. Front Med (Lausanne). 2021;8:654956.
- Yu L, Yang B, Xu Q, Teng Y, Xue Z. A study on the timing of uterine artery embolization followed by pregnancy excision for cesarean scar pregnancy: a prospective study in China. BMC Pregnancy Childbirth. 2021;21(1):697.
- Marchand GJ, Masoud AT, Coriell C, Ulibarri H, Parise J, Arroyo A, et al. Treatment of cesarean scar ectopic pregnancy in China with uterine artery embolization—a systematic review and meta- analysis. J Clin Med. 2022;11(24):7393.
- Wang X, Yang B, Chen W, Chen J. Clinical efficacy and re- pregnancy outcomes of patients with previous cesarean scar pregnancy treated with either high-intensity focused ultrasound or uterine artery embolization before ultrasound-guided dilatation and curettage: a retrospective cohort study. BMC Pregnancy and Childbirth. 2023;23(1):85.
- Du Z, Xu W, Lu J, Li C. Comparison of clinical safety and efficacy of ultrasound-guided local lauromacrogol injection versus uterine artery embolization in the treatment of caesarean scar pregnancy: a systematic review and meta-analysis. BMC Pregnancy Childbirth. 2023;23(1):149.
- Pecorino B, Scibilia G, Mignosa B, Teodoro MC, Chiofalo B, Scollo P. Dilatation and curettage after uterine artery embolization versus methotrexate injection for the treatment of cesarean scar pregnancy: A single-center experience. Medicina. 2024;60(3):487.
- Xiao J, Shi Z, Zhou J, Ye J, Zhu J, Zhou X, et al. Cesarean Scar Pregnancy: Comparing the Efficacy and Tolerability of Treatment with High-Intensity Focused Ultrasound and Uterine Artery Embolization. Ultrasound Med Biol. 2017;43(3):640–7.
- Li X, Niu H, Li J, Zhang L, Qu Q. Clinical assessment of uterine artery embolization combined with curettage when treating patients with cesarean scar pregnancy: A retrospective study of 169 cases. J Obstet Gynaecol Res. 2020;46(7):1110–6.
- Sorrentino F, De Feo V, Stabile G, Tinelli R, D'Alterio MN, Ricci G, et al. Cesarean scar pregnancy treated by artery embolization combined with diode laser: A novel approach for a rare disease. Medicina (Kaunas). 2021;57(5):411.
How to Cite This Article
Vancouver
Chellamuthu J, Meignanamoorthy G, Hameed J. Uterine artery embolization: A novel frontier in the treatment of caesarean scar pregnancy [Internet]. Indian J Obstet Gynecol Res. 2025 [cited 2025 Oct 03];12(3):362-368. Available from: https://doi.org/10.18231/j.ijogr.v.12.i.3.2
APA
Chellamuthu, J., Meignanamoorthy, G., Hameed, J. (2025). Uterine artery embolization: A novel frontier in the treatment of caesarean scar pregnancy. Indian J Obstet Gynecol Res, 12(3), 362-368. https://doi.org/10.18231/j.ijogr.v.12.i.3.2
MLA
Chellamuthu, Jothikala, Meignanamoorthy, Gomathi, Hameed, Jamila. "Uterine artery embolization: A novel frontier in the treatment of caesarean scar pregnancy." Indian J Obstet Gynecol Res, vol. 12, no. 3, 2025, pp. 362-368. https://doi.org/10.18231/j.ijogr.v.12.i.3.2
Chicago
Chellamuthu, J., Meignanamoorthy, G., Hameed, J.. "Uterine artery embolization: A novel frontier in the treatment of caesarean scar pregnancy." Indian J Obstet Gynecol Res 12, no. 3 (2025): 362-368. https://doi.org/10.18231/j.ijogr.v.12.i.3.2