Risk factors associated with early and late onset preeclampsia in national referral centre hospital

• Author Details:   
• Johnny . ^*
• Judi Januadi Endjun
• Jessica Nathalia

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Background: To investigate what conditions or risk factors can cause early onset preeclampsia and late onset preeclampsia.

Materials and Methods: This was an retrospective analysis with a cross sectional design. The data was collected using medical records, which include maternal data, medical history, and obstetric history. Risk factors associated with preeclampsia were studied between early onset preeclampsia and late onset preeclampsia. Risk factors were analyzed by logistic regression analysis.

Results: The data obtained showed that all samples in the early onset preeclampsia group had a previous history of hypertension, gestational diabetes and diabetes mellitus. Risk factors associated with early onset preeclampsia were maternal age (Odd ratio [OR] 1.61, 95% Confident Interval [CI] 1.24-5.12), chronic hypertension (OR 5.97, 95% CI 3.10-8.37), history of preeclampsia with incident (OR 2.53, 95% CI 1.46-6.36). Risk factors associated with late onset preeclampsia were maternal age (OR 1.25, 95% CI 2.12-6.31), chronic hypertension (OR 2.06, 95% CI 1.41-3.92), BMI (OR 3.27, 95% CI 1.95-7.11).

Conclusion: Although they share some etiological features, they also differ with respect to other risk factors. The two preeclampsia types should be treated as distinct entities from an etiological standpoint.