- Visibility 521 Views
- Downloads 562 Downloads
- Permissions
- DOI 10.18231/j.ijogr.v.12.i.3.22
-
CrossMark
- Citation
Clinical profile of ovarian tumours at a tertiary centre in north Karnataka
- Author Details:
-
Shradha Tondare
-
Usha Doddamani
-
Sheetal K
-
Sangamesh T *
Background: Ovarian neoplasms are a significant cause of morbidity and mortality in gynecologic oncology due to their diverse histopathological profiles and late diagnosis. Given the high mortality rates associated with ovarian cancer, this study aims to analyze the clinical profile of ovarian tumours at a tertiary care centre to improve early detection and management strategies.
Materials and Methods: This retrospective study was conducted over two years at the Department of Obstetrics and Gynaecology, focusing on women of reproductive to postmenopausal age with suspected ovarian tumours confirmed by ultrasound. Data were collected on patient demographics, clinical presentation, tumour markers, imaging, surgical interventions, and histopathological findings.
Results: The majority of patients (34%) were aged 21-30, and 78% were multiparous. Abdominal pain was the most common presenting symptom (48%). Most tumours were unilateral (94%), and 92% of participants had normal or undetectable CA-125 levels. Large ovarian cysts were identified in 44% of cases, with benign mucinous cystadenomas being the most frequent histopathological diagnosis (24%). Laparotomy with cystectomy was the most commonly performed surgical procedure (30%).
Conclusion: This study provides a comprehensive clinical profile of ovarian tumours at a tertiary care centre, highlighting the predominant symptoms, imaging findings, and histopathological diagnoses. The findings underscore the importance of clinical vigilance and the use of diagnostic tools in identifying ovarian tumours. Increased awareness and targeted diagnostic strategies, particularly for younger women, are essential to reduce the burden of ovarian cancer.
References
- Young RH. The ovary. In: Sternberg S, editor. Diagnostic Surgical Pathology. 17th ed. New York: Raven Press; 1994. p. 2195.
- Montag A, Kumar V. The female genital system and breast. In: Robbins Basic Pathology. 9th ed. Philadelphia: Saunders Elsevier;
- p. 991–1042.
- Mankar DV, Jain GK. Histopathological Profile of Ovarian tumours. A twelve year experience. Muller J Med Sci Res. 2015;6(2):107–11.
- Murthy NS, Shalini S, Suman G, Pruthvish S, Mathew A. Changing trends in incidence of ovarian cancer - the Indian scenario. Asian Pac J Cancer Prev. 2009;10(6):1025–30.
- Mondal SK, Banyopadhyay R, Nag DR, Roychowdhury S, Mondal PK, Sinha SK. Histologic pattern, bilaterality and clinical evaluation of 957 ovarian neoplasms: a 10-year study in a tertiary hospital of eastern India. J Cancer Res Ther. 2011;7(4):433–7.
- Jha R, Karki S. Histological pattern of ovarian tumors and their age distribution. Nepal Med Coll J. 2008;10(2):81–5.
- Patel A, Patel VN. Study of frequency and histopathological pattern of soft tissue tumours in tertiary care centre of Gandhinagar, Gujarat. Trop J Pathol Microbiol. 2019;5(1):20–5.
- Geomini P, Kruitwagen R, Bremer GL, Cnossen J, Mol BWJ. The accuracy of risk scores in predicting ovarian malignancy: a systematic review. Obstet Gynecol. 2009;113(2 Pt 1):384–94.
- Kanthikar SN, Dravid NV, Deore PN, Nikumbh DB, Suryawanshi KH. Clinico-histopathological analysis of neoplastic and non- neoplastic lesions of the ovary: a 3-year prospective study in dhule, north maharashtra, India. J Clin Diagn Res. 2014;8(8):FC04–7.
- Gupta N, Bisht D, Agarwal AK, Sharma VK. Retrospective and prospective study of ovarian tumours and tumour-like lesions. Indian J Pathol Microbiol. 2007;50(3):525–7.
- Gupta N, Yadav M, Gupta V, Chaudhary D, Patne SCU. Distribution of various histopathological types of ovarian tumors: A study of 212 cases from a tertiary care center of Eastern Uttar Pradesh. J Lab Physicians. 2019;11(1):75–81.
- Sawant A, Mahajan S. Histopathological study of ovarian lesions at a tertiary health care institute. MVP J Med Sci. 2017 May 22;4(1):26–9.
- Prakash A, Chinthakindi S, Duraiswami R, V I. Histopathological study of ovarian lesions in a tertiary care center in Hyderabad, India: a retrospective five-year study. Int J Adv Med. 2017;4(3):745–9.
- Sheikh S, Bashir H, Farooq S, Beigh A, Manzoor F, Reshi R. Histopathological spectrum of ovarian tumors from a referral hospital in Kashmir valley, Jammu and Kashmir, India. Int J Res Med Sci. 2017;5(5):2110–4.
- Jacoby VL, Grady D, Wactawski-Wende J, Manson JE, Allison MA, Kuppermann M, et al. Oophorectomy vs ovarian conservation with hysterectomy: cardiovascular disease, hip fracture, and cancer in the Women's Health Initiative Observational Study. Arch Intern Med. 2011;171(8):760–8.
- Modi PJ, Bhalodia JN, Shah NM. Histopathological analysis of non- neoplastic lesions of ovary: A study at tertiary care hospital in western region of India. Int J Med Sci Public Health. 2018;7(10):843–7.
How to Cite This Article
Vancouver
Tondare S, Doddamani U, K S, T S. Clinical profile of ovarian tumours at a tertiary centre in north Karnataka [Internet]. Indian J Obstet Gynecol Res. 2025 [cited 2025 Oct 03];12(3):495-502. Available from: https://doi.org/10.18231/j.ijogr.v.12.i.3.22
APA
Tondare, S., Doddamani, U., K, S., T, S. (2025). Clinical profile of ovarian tumours at a tertiary centre in north Karnataka. Indian J Obstet Gynecol Res, 12(3), 495-502. https://doi.org/10.18231/j.ijogr.v.12.i.3.22
MLA
Tondare, Shradha, Doddamani, Usha, K, Sheetal, T, Sangamesh. "Clinical profile of ovarian tumours at a tertiary centre in north Karnataka." Indian J Obstet Gynecol Res, vol. 12, no. 3, 2025, pp. 495-502. https://doi.org/10.18231/j.ijogr.v.12.i.3.22
Chicago
Tondare, S., Doddamani, U., K, S., T, S.. "Clinical profile of ovarian tumours at a tertiary centre in north Karnataka." Indian J Obstet Gynecol Res 12, no. 3 (2025): 495-502. https://doi.org/10.18231/j.ijogr.v.12.i.3.22