Background: Ovarian neoplasms are a significant cause of morbidity and mortality in gynecologic oncology due to their diverse histopathological profiles and late diagnosis. Given the high mortality rates associated with ovarian cancer, this study aims to analyze the clinical profile of ovarian tumours at a tertiary care centre to improve early detection and management strategies.
Materials and Methods: This retrospective study was conducted over two years at the Department of Obstetrics and Gynaecology, focusing on women of reproductive to postmenopausal age with suspected ovarian tumours confirmed by ultrasound. Data were collected on patient demographics, clinical presentation, tumour markers, imaging, surgical interventions, and histopathological findings.
Results: The majority of patients (34%) were aged 21-30, and 78% were multiparous. Abdominal pain was the most common presenting symptom (48%). Most tumours were unilateral (94%), and 92% of participants had normal or undetectable CA-125 levels. Large ovarian cysts were identified in 44% of cases, with benign mucinous cystadenomas being the most frequent histopathological diagnosis (24%). Laparotomy with cystectomy was the most commonly performed surgical procedure (30%).
Conclusion: This study provides a comprehensive clinical profile of ovarian tumours at a tertiary care centre, highlighting the predominant symptoms, imaging findings, and histopathological diagnoses. The findings underscore the importance of clinical vigilance and the use of diagnostic tools in identifying ovarian tumours. Increased awareness and targeted diagnostic strategies, particularly for younger women, are essential to reduce the burden of ovarian cancer.